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In a phase I study, the goal is to determine the best way to administer a drug and the maximum dose tolerated with the fewest side effects. Phase 0 studies expose a small number of people to low doses of a drug over a limited period of time -- seven days or less. As the name implies, a phase 0 trial precedes "phase I" testing, traditionally the first step in the process of human drug testing. Scientists look at how the body reacts to the drug and how it acts in the body. "We want to find out if they're ineffective in the smallest number of patients and get definitive information as niven in the development process as possible," said Dr. Doroshow, director of the division of cancer treatment and diagnosis at the National Cancer Institute in Bethesda, Md. If the drug hits its intended target without producing significant side effects, the next phase can be expedited. If not, a decision can be made to scrap the. The new model, a so-called "phase 0" clinical trial, promises to streamline the costly and time-consuming drug development process, helping to deliver good drugs to people who need them more quickly. | orange sol orange sol 1oz plus de-solv-it orange sol orange sol 1oz contractor solvent orange sol 22608 de-solv-it citrus solution cleaner orange sol orange sol gal contractor solvent a020847lq - non-aerosol liqui-sol ultra-force 11 safe solv 41772 - pine-sol orange energ 144oz all pur sol overtime 26" duffel - orange silver hex covercraft front end masks - hood protector w/ bug deflector 93-95 honda del sol s / del sol si;;96-98 honda del sol zex nitrous oxide kits - wet nitrous kit (55-75 hp) 93-97 honda del sol s / del sol si / del sol dohc vtec 41772ea - clorox pine sol all-purpose cleaner - liquid solution - 144fl oz - orange zex nitrous oxide kits - wet nitrous kit - polished bottle (55-75 hp) 93-97 honda del sol s / del sol si / del sol dohc vtec nology spark plug wires - orange 92-95 honda del sol s 1.5l / 1.6l 4 cylinder (except vtec) |