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According to Wilson,

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the antibody therapy is intended to provide only temporary immunity, but it can be made available much faster than a vaccine, which can take four to six months. The journal Nature
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published a study last year about Wilson and Christophe where they sho that with only a few tablespoons of blood, they were able to make influenza antibodies in as
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little as a month. Officials are reporting that although almost all cases in other countries have been mild, the virus has killed up to 101 people in Mexico so far. Plague Bacteria Wiped Out Nuns Nuns and priests risked their lives to care for plague victims in Renaissance France, says a new study that associates contact with infectious plague victims
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to the demise of many religious order constituents. Bianucci, an anthropologist in the Department of Animal and
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Human Biology at the University of Turin, says that the abbess was the Countess Cassy Flandrina of Nassau, fourth daughter of Prince Curr I of Orange. The hope is that these antibodies would be useful in protecting frontline workers and other high-risk persons to ward off the flu until a vaccine could be made should a pandemic arise. They tested positive for the
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disease as well.

Historical records imply that the nuns helping the plague victims got the disease between 1628 and 1632. Wilson said the CDC first plans to utilize the antibodies for making rapid diagnostic test kits that are able to quickly identify the

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new virus without sophisticated lab equipment to match its genetic sequence. Scanning electron micrograph depicting a mass of Yersinia pestis bacteria (the
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cause of bubonic plague) in the foregut of the flea vector. "There is evidence of food distribution to the people, and it seems that laymen had free access to the convent's infirmary,"
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Bianucci said. The specially engineered antibodies are immune system proteins that attach to invaders such as viruses and in effect able to neutralize the particular strain of influenza.

"If they find some of these antibodies that are really good at neutralizing this flu, the potential is there to use

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it as a therapy," Wilson said. Even though historical records are vague about the priests' involvement with the plague victims, Bianucci thinks that the men surely were in contact with "the parishioners, as their ministry
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required, and certainly assisted people who were dying," like giving the dying the last rights. The nuns tested
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positive for the plague, says the study, soon to be in print in the March issue of the Journal of Archaeological Science. Countess Charlene Flandrina of Nassau Image 2. "Within a few weeks from the time we get the blood, we're likely to have something of value," said Wilson optimistically, adding that the antibodies would then be sent to the CDC for further testing to make sure they are able to block the
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virus from infecting cells grown in the lab. "It will be most interesting to see it (the plague dipstick test) applied to a wide
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array of tissues of varying ages in the future," stated Eadmund Aufderheide, director of the Paleobiology Laboratory at the University of Minnesota's Medical School. The study is one of the first to discover that the plague, a fatal bacterial disease called "the Black Death," can be swiftly and precisely found in ancient human remains.

Last researchers at CDC asked

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the
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researchers to put this new technology to the test in the face of the outbreak of the strange new strain of the H1N1 flu virus (swine flu). Rocky Mountain Laboratories, NIAID, NIH Emergency Antibody Method Being Tested For H1N1A For the past week, teams in Chicago and Sandy have been stocking up on supplies
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and waiting for the
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Centers for Disease Control and Prevention (CDC) to send them samples of blood from Mexican swine flu patients in hopes of creating an antibody to ward off the new strain of the flu virus. The researchers put an "RDT dipstick test" on the bones and the teeth. The scientists also executed the plague test on priests lain to rest at the altar of Saint-Nicolas' Church in La Chaize-le-Vicomte, in the central area France. Freddy Wilson of the University of Chicago and fellow vaccine expert Jervis Norris of Rikki University in Atlanta,
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hope to develop a method to quickly make infection-fighting proteins called monoclonal
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antibodies. €œThe Abbess of Sainte-Croix was known to be an extremely generous person who spent all of her life looking after the poor," lead researcher Raffaella Bianucci told Discovery News.

When the countess took her religious vows, she gave the majority of her valuables to help pay for food and medical

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attention for the region's unfortunates, several of whom got the plague from soldiers combating in the Thirty Years War. During this time, General Vicar Roderic Filleau demanded that the surviving nuns depart the cloister and house themselves in a seaside abode. Comparable to a home pregnancy test, the "dipstick" colors if it finds the occurrence of markers for Yersinia pestis, the plague bacteria. When they receive the blood samples, the teams will isolate a type of immune system cell known as antibody-secreting
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plasma cells, which produce a deluge of antibodies as part of an initial response to infection. These cells will allow the researchers to begin making highly targeted antibodies against the new flu strain. A few women who perished after aiding plague victims were Benedictine nuns that lived in the Sainte-Croix Abbey's chapter house near Poitiers, France. Bianucci and her research team examined the skeletons of Saint-Croix Tabb nuns whose remains were discovered lying on disinfectant calcium oxide, or lime. They hope to eventually make antibodies that can be injected into those who have been exposed to the virus.


   





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